Society for Free Radical Research - Europe

December News from the ECR subcommittee

Dear fellow researchers, 

As we wrap up the year and step into the festive season, we’re delighted to bring you the final newsletter of 2025, filled with exciting updates from the SFRR-E ECR community. It has been a wonderful year of science, connection, and collaboration, and we’re grateful to everyone who has been part of it.

In this issue, we’re pleased to announce our next SFRR-E ECR Webinar, taking place on 13th January, kicking off the new year with fresh ideas and inspiration. We also celebrate the awardees of the 3rd PhD Symposium, recognising outstanding contributions from our early-career researchers.

Looking ahead to 2026, you’ll find all the essential information about the SFRR-E Travel Awards for the Annual Meeting in Mainz, a fantastic opportunity to present your work and connect with the wider redox community. We also highlight the SFRR-E / OCC Early Career Researcher (ECR) Fellowships - 2026, supporting the next generation of redox scientists.

Finally, we share a recap of our December webinar, featuring two excellent talks packed with valuable insights for early-career scientists.

And of course, as always, you’ll also find upcoming deadlines, interesting events, paper calls, fresh redox reads, and job opportunities you won’t want to miss.

We hope this festive edition brings you both inspiration and a moment to reflect on a successful year. Wishing you a joyful holiday season and a bright start to 2026!


Next SFRR-E ECR Webinar - January 13th!

We’re thrilled to keep the momentum going with the fifth session of the SFRR-E ECR webinar series, “Emerging Leaders in Redox Biology”, taking place on January 13th, 2026! This series is dedicated to showcasing early-career researchers who are pushing the boundaries of redox biology. We’re looking forward to another engaging afternoon of learning, discussion, and connection. This time, we’ll explore the captivating topic of “Computational Redox Biology”, with presentations from two exceptional researchers - Cameron Schmidt and Karen Guerrero Vazquez. Join us at 15:00 CET for an exciting deep dive into cutting-edge redox research!


NAD(P)H Redox State as a Mechanism for Fine Tuning Microswimmer Search Strategies

Cameron Schmidt, PhD

Department of Biology, East Carolina University, USA

Dr. Cameron A. Schmidt is an Assistant Professor in the Department of Biology at East Carolina University, Greenville, NC. His research seeks to understand how energy and information intersect to inform the emergent behaviors of cells and cell collectives. His interdisciplinary group explores these questions by combining mathematical/computational modeling with laboratory experiments primarily focused on the biology of mammalian reproduction. Dr. Schmidt’s academic journey began with a B.S. in Biology, complemented by minors in Applied Mathematics and Chemistry from The University of Akron. He received a Ph.D. in Physiology from East Carolina University in 2018 and remained at ECU during his tenure as an NIH Ruth L. Kirchstein Postdoctoral Fellow in Bioenergetics and Redox Systems Biology where he studied cellular energy transduction and mitochondrial energetics in models of cancer and metabolic disease. His current NIH supported work aims to improve sperm selection for assisted reproductive therapies.

 


Karen Guerrero Vazquez, PhD

University of Galway, Ireland

Karen obtained her computer systems engineering degree and her master's in computer science in Mexico, and in 2025 earned her PhD in genomics data science at the University of Galway, Ireland. She is interested in integrating computational tools to address biological questions, especially in Machine Learning and algorithm design. She cares about computer engineering values and is especially interested in the effects of ageing in humans.

A significant part of her doctoral work was the development of the miRKat Suite, an integrated computational platform designed to help researchers prioritise therapeutic microRNA targets, and the development of predictive models to identify signature genes for ageing muscle from high-dimensional transcriptomic data. Her work has also explored the role of oxidised microRNAs.

Don’t miss this inspiring continuation of the series! Mark your calendars, spread the word, and join us online for a stimulating session! We look forward to seeing you there and to another season of groundbreaking science and lively discussions with the SFRR-E ECR community.

 

3rd PhD Symposium — Celebrating Our Awardees!

We are delighted to announce the awardees of the 3rd edition of the PhD Symposium “Redox Relay Race: PhD Students on the Move”, held on 18–19 November 2025. After two truly inspiring days of excellent science, stimulating discussions, and impressive enthusiasm, the awards go to Lucas Carvalho, Shani Doron, and Valentin Kapferer, whose outstanding contributions particularly stood out.

We would also like to warmly thank all participants for the high quality of their presentations, their engagement, and the vibrant, collaborative spirit they brought to the symposium. Your work highlights the strength and diversity of the redox community, and we strongly encourage you to keep pushing boundaries, sharing ideas, and shaping the future of the field.

 

SFRR-E / OCC Early Career Researcher (ECR) Fellowships – 2026

Ready to take the next step in your redox research career?

We are pleased to announce the 2026 Call for applications for the SFRR-E / OCC Early Career Researcher (ECR) Fellowships. These Fellowships aim to support early career researchers by providing up to €10,000 for research or seed funding for a new project in the field of redox biology, to be completed within a 12-month period. The number of Fellowships awarded will depend on the quality of the applications received.

The Fellowship funding cannot be used to cover salary costs and must not overlap with existing funding. Applicants are expected to clearly explain how receiving this Fellowship will support their future career development and research goals.

Who can apply?

Applications are open to Early Career Researchers who are current financial members of SFRR-E and whose proposed projects are relevant to redox research. Full eligibility criteria are detailed in the application guidelines.

How to apply

Applicants must submit their application using the official form available through the SFRR-E member area at https://www.sfrr-europe.org. To access the application form and guidelines, log in via “Member login & renewal” under the Membership menu and select the “SFRR-E / OCC ECR Fellowship” option in the blue menu on the left. This page also allows applicants to join the Society or renew their membership, if required.

Applications should be submitted as a single PDF file, including all required attachments, through the SFRR-E member area. Each application will be evaluated by three independent peer reviewers appointed by SFRR-E.

Important date

Application deadline: 23 January 2026

Take this opportunity to develop new ideas, generate preliminary data, and move your redox research forward.

 

SFRR-E Travel Awards – Mainz 2026

Ready to take your science on the road?

We’re excited to announce that SFRR-E Travel Awards will be available for students and postdocs to attend the 2026 SFRR-E Annual Meeting “Redox Biology, Environment Exposures and Lifestyle”, taking place in Mainz, Germany (3-5 June 2026).

What’s on offer?

Europe-based applicants: €400 travel grants for PhD students or postdocs (≤5 years post-PhD, non-permanent positions).

Outside Europe: €900 travel awards for SFRR-E or Regional SFRR Society members under the same conditions.

(Note: previous SFRR-E Travel Grant or Young Investigator Award recipients are not eligible.)

Who can apply?

PhD students and postdocs who are current members of SFRR-E (or a Regional SFRR Society outside Europe) and meet the eligibility criteria above.

How to apply

Submit your application as a single PDF via the SFRR-E intranet https://intranet.sfrr-europe.org and select the option “Travel Awards for SFRR-E Mainz” in the menu on the left.

Your PDF should include:

    • CV (max 2 pages, including PhD start/award date)
    • Motivation letter
    • Abstract intended for presentation

(Incomplete applications will not be considered.)

Important dates

  • Deadline: 12 January 2026
  • Results announced: before 26 January 2026 (abstract submission deadline)

Funds will be transferred after proof of registration and abstract submission.

Conference website: www.sfrremainz2026.com

Questions? Contact This email address is being protected from spambots. You need JavaScript enabled to view it.

Don’t miss your chance to join us in Mainz - and take your redox research further than ever!

 

Summary of December’s webinar:

On December’s webinar we learnt about ”Redox mechanisms in Aging” with two wonderful talks by Claudia Lennicke and Anna Gioran. If you didn’t have a chance to follow the webinar, here’s a summary for you.


Profiling of cysteine oxidation by unbiased redox proteomics reveals sex-dependent patterns during ageing

Claudia Lennicke, PhD

MRC Laboratory Institute of Medical Sciences (LMS), Institute of Clinical Sciences, Imperial College London, UK

Claudia presented her work using Drosophila melanogaster to identify specific redox-sensitive proteins that modulate lifespan. Through unbiased redox proteomics combined with targeted genetic approaches, her research demonstrated that oxidative modifications are not uniformly detrimental but instead act as regulated signals that vary across tissues, sexes, and age. These findings support the concept that finely tuned redox signaling, rather than global antioxidant capacity, is a key determinant of metabolic homeostasis and longevity.


When mitochondria falter: Impact on longevity and link to proteostasis

Anna Gioran, PhD

Chair of Biomaterials, University of Bayreuth, Germany

Anna focused on the role of mitochondrial redox metabolism in aging and disease, emphasizing how mitochondrial dysfunction perturbs redox balance, proteostasis, and organismal health. Using genetically and metabolically defined models, her work illustrated how defects in mitochondrial metabolism propagate redox stress, impacting cellular resilience and aging trajectories. She further discussed the need for metabolically relevant experimental systems to capture redox–mitochondria interactions, underscoring how improved disease-relevant models can enhance the identification of redox-targeted interventions.

Remember that you can also watch recordings of the webinars through the SFRR-E intranet!

Want to know more about what we do? You’ll find all the info about the ECR Subcommittee on the SFRR-E website.

For regular updates, follow us on Instagram (@sfrr_ecr), Bluesky (@sfrre-ecr.bsky.social‬) Twitter/X (@SFRR_Europe), and LinkedIn (SFRR-E).

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. - we’d love to hear from you!

 - The ECR Subcommittee Team

 

Upcoming Events You Won’t Want to Miss:

SFRR-E Annual Meeting

  • Redox Biology, environmental exposures and lifestyle
  • Mainz, Germany | 3-5 June 2026
  • Abstract deadline: 14 February | Early registration deadline: 21 March
  • More info

 

The Society for Redox Research Australasia & International Human Peroxidase Joint Meeting

  • Christchurch, New Zealand | 2-4 September 2026
  • Abstract deadline: 1 July | Early registration deadline: 17 July
  • More info

 

17th International Conference on Reactive Oxygen and Nitrogen Species in Plants

  • Granada, Spain | 9-11 September 2026
  • Abstract deadline: 2 May | Registration deadline: 30 June
  • More info

 

23rd Biennial Meeting of SFRR International 2027

  • Redox Frontiers 2027: Expanding Horizons with New Concepts and Technologies
  • Sendai, Japan | 28-31 March 2027
  • More information coming soon
  • More info

 

Redox Reads Worth Your Time:

Research Articles

Sung, E., Murakami, S., Morita, M., et al. Mitochondria regulate the cell fate decisions of megakaryocyte-erythroid progenitors. Stem Cell Reports (2025). https://doi.org/10.1016/j.stemcr.2025.102720

della Volpe, L., Lee, A.J., Antoszewski, M. et al. Inhibiting ferroptosis enhances ex vivo expansion of human haematopoietic stem cells. Nat Cell Biol (2025). https://doi.org/10.1038/s41556-025-01814-7

Shakir D., Batie M., Kwok C.S., et al. NF-kappaB is a central regulator of hypoxia-induced gene expression. EMBO Rep (2025). https://doi.org/10.1038/s44319-025-00651-x

Zhang, JJ., Tian, RF., Song, CG. et al. Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer. Nat Commun (2025). https://doi.org/10.1038/s41467-025-67091-y

Hu, Y., Li, Z., Li, M., et al. Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression. Mol Cell (2025). https://doi.org/10.1016/j.molcel.2025.11.023

Toshniwal, A.G., Lam, G., Bott, A.J., et al. The fate of pyruvate dictates cell growth by modulating cellular redox potential. Elife (2025). https://doi.org/10.7554/elife.103705

 

Reviews to Think About

O'Donnell, V.B. & Bochkov, V. Oxidized phospholipids in ferroptosis, immunity and inflammation. Redox Biochem Chem (2025). https://doi.org/10.1016/j.rbc.2025.100061

Tian, K., Xiong, T., Zeng, D., et al. Impact of reactive oxygen species on bone regeneration in diabetes: Mechanisms and therapeutic strategies. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103941

 

New Protocols

Miljkovic, J.L., Burger, N., Yu, C.S. et al. Simultaneous and sensitive quantification of protein and low molecular weight persulfides, polysulfides and H2S in biological samples. Nat Commun (2025). https://doi.org/10.1038/s41467-025-66795-5

Penkov, S., Bendoula, G.L. & Fedorova, M. Strategies to minimize artificial lipid oxidation in mass spectrometry based epilipidomics analysis. Methods Enzymol (2025). https://doi.org/10.1016/bs.mie.2025.11.019

  

Preprints We’re Watching

Furusawa, T., Gujar, V., Sharma, S., et al. Peroxiredoxin 1 safeguards the nucleolar genome from oxidative damage. BioRxiv (2025). https://doi.org/10.1101/2025.11.12.685177

Castejon-Vega, B., Fernandez-Guerrero, I., Yu, Y., et al. Developmental Programming of Mitochondrial Function Limits Lifespan in Short-Lived Animals. BioRxiv (2025). https://doi.org/10.1101/2023.06.23.546283

 

Call for Papers:

Journal: Redox Biochemistry and Chemistry

  • Special Issue: Redox Metals in Health and Disease
  • Submission Deadline: 31 December 2025
  • More info

 

Journal: Redox Biology

  • Special Issue: The role of nitric oxide in redox signaling and disease: shaping the future with emerging leaders
  • Submission Deadline: 31 December 2025
  • More info

 

Redox Jobs Board:

Type of position: Group Leader

Type of position: Postdoctoral position

Got a position open for a PhD student, postdoc, or technician in redox research?

Want to feature it in our next newsletter? Send us the details at This email address is being protected from spambots. You need JavaScript enabled to view it. including:

  • Type of position (PhD student, Postdoc, etc)
  • Research topic
  • Institute or university
  • Deadline
  • Contact info
  • Additional details or link

November News from the ECR subcommittee

Dear fellow researchers, 

As we head toward the end of the year, we’re back with another round of exciting updates from the SFRR-E ECR community!

In this issue, we’re excited to announce our next webinar taking place on 2nd December. We also bring you a recap of the 3rd PhD Symposium, two fantastic days of cutting-edge redox science delivered by an inspiring group of emerging researchers. You’ll also find everything you need to know about the SFRR-E Travel Awards for the 2026 Annual Meeting in Mainz, an excellent opportunity to share your work with the wider redox community.

This month, we also share the highlights from the November webinar, featuring two excellent talks packed with insights for early-career scientists. And don’t miss our Meet the Expert section, where we had the pleasure of interviewing Prof. Isabel Fabregat - a deep dive into career paths, scientific inspiration, and her vision for the future of redox biology.

And of course, as always, you’ll also find upcoming deadlines, interesting events, paper calls, fresh redox reads, and job opportunities you won’t want to miss.

 

Next SFRR-E ECR Webinar – December 2nd!

We’re thrilled to keep the momentum going with the fourth session of the SFRR-E ECR webinar series, “Emerging Leaders in Redox Biology”, taking place on December 2nd, 2025! This series is dedicated to showcasing early-career researchers who are pushing the boundaries of redox biology. We’re looking forward to another engaging afternoon of learning, discussion, and connection. This time, we’ll explore the captivating topic of “Redox mechanisms in Aging”, with presentations from two exceptional researchers - Claudia Lennicke and Anna Gioran. Join us at 15:00 CET for an exciting deep dive into cutting-edge redox research!


Profiling of cysteine oxidation by unbiased redox proteomics reveals sex-dependent patterns during ageing

Claudia Lennicke, PhD

MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Imperial College London, UK

Dr Claudia Lennicke is originally from Germany and obtained her PhD from the Martin Luther University Halle-Wittenberg, where she developed a strong interest in redox signalling. Her doctoral work focused on how selenocompounds shape cellular redox balance and how tumours evade immune surveillance. In 2018, Claudia joined the Cochemé Lab at the MRC Laboratory of Medical Sciences (LMS) in London as a postdoctoral researcher. There, she investigates fundamental mechanisms of redox regulation in metabolism and ageing using Drosophila melanogaster. Claudia is now a devoted fan of Drosophila, and has been involved in many outreach and engagement initiatives, highlighting the power and tractability of the fly to study longevity. Her research is focused on discovering specific redox-sensitive proteins involved in lifespan regulation, using a combination of unbiased redox proteomics and targeted genetic knock-in approaches, exploring how oxidative processes shift across tissues and sexes during ageing.

 


When mitochondria falter: Impact on longevity and link to proteostasis

Anna Gioran, PhD

Chair of Biomaterials, University of Bayreuth, Germany

Anna's interests mainly revolve around the development of mitochondrial disease models that will help understand the disease and, most importantly, be useful in the detection of counteracting compounds. She studied biology at the University of Athens in Greece and moved to the DZNE, Bonn, Germany for her PhD. During her time as a PhD student (2012-2015) she studied the effects of mitochondrial deficiency on the nervous system of the nematode C. elegans. During her first postdoctoral work she broadened her focus and looked at the overall consequences of mitochondrial deficiency on the metabolism of the nematode. At the same time she participated in several projects that attempted to model mitochondrial disease in nematode, cellular and mouse models. After this, she occupied another postdoctoral position for the purposes of which she studied the role of mitochondria in proteostasis-related longevity paradigms. Her experience made her realize the serious lack of accurate models of mitochondrial diseases which are necessary for the discovery of treatments. To address this major gap, she has now moved to the University of Bayreuth where, in collaboration with a team of bioengineers, she is attempting to develop metabolically accurate engineered tissue with the ultimate goal to generate in vitro models of mitochondrial disease. Despite years of studying mitochondria, Anna admits they still manage to surprise her-usually right after she has told someone an experiment “should be straightforward.”.

Don’t miss this inspiring continuation of the series! Mark your calendars, spread the word, and join us online for a stimulating session! We look forward to seeing you there and to another season of groundbreaking science and lively discussions with the SFRR-E ECR community.

How can I join the webinar?

https://us06web.zoom.us/j/86469731540?pwd=cQW0yK5sNCPXO5sSOcaoBHaZPy2Tu8.1
Passcode: 433382

 

3rd PhD Symposium — A Fantastic Edition!

Our 3rd edition of the PhD Symposium “Redox Relay Race: PhD Students on the Move”, held on 18-19 November 2025, was truly inspiring! We enjoyed two fantastic days of science, filled with high-quality presentations, fresh perspectives, and outstanding enthusiasm from all participating students. Their work showcased the diversity and excellence of early-career research across the redox field, and we couldn’t be prouder of the community they represent.

Stay tuned - the winners of this year’s awards will be announced on Tuesday 2nd December, during our next ECR webinar!

 

SFRR-E Travel Awards – Mainz 2026

Ready to take your science on the road?

We’re excited to announce that SFRR-E Travel Awards will be available for students and postdocs to attend the 2026 SFRR-E Annual Meeting “Redox Biology, Environment Exposures and Lifestyle”, taking place in Mainz, Germany (3-5 June 2026).

What’s on offer?

  • Europe-based applicants: €400 travel grants for PhD students or postdocs (≤5 years post-PhD, non-permanent positions).
  • Outside Europe: €900 travel awards for SFRR-E or Regional SFRR Society members under the same conditions.
  • (Note: previous SFRR-E Travel Grant or Young Investigator Award recipients are not eligible.)

Who can apply?

  • PhD students and postdocs who are current members of SFRR-E (or a Regional SFRR Society outside Europe) and meet the eligibility criteria above.

How to apply

  • Submit your application as a single PDF via the SFRR-E intranet (https://intranet.sfrr-europe.org) and select the option “Travel Awards for SFRR-E Mainz” in the menu on the left.
  • Your PDF should include:
  • CV (max 2 pages, including PhD start/award date)
  • Motivation letter
  • Abstract intended for presentation
  • (Incomplete applications will not be considered.)

Important dates

  • Deadline: 12 January 2026
  • Results announced: before 26 January 2026 (abstract submission deadline)
  • Funds will be transferred after proof of registration and abstract submission.
  • Conference website: www.sfrremainz2026.com
  • Questions? Contact This email address is being protected from spambots. You need JavaScript enabled to view it.

Don’t miss your chance to join us in Mainz - and take your redox research further than ever!

 

Interview with Dr. Isabel Fabregat: How to Craft a Competitive Scientific Project Proposal

About Dr. Isabel Fabregat

Dr. Isabel Fabregat is a leading researcher in cancer biology and a dedicated mentor to early-career scientists. She leads a research group at IDIBELL (Institut d’Investigació Biomèdica de Bellvitge) in Barcelona, Spain. Throughout her career, she has combined cutting-edge biomedical research with an unwavering commitment to mentoring young scientists.

In this conversation, she shares her practical advice and reflections on how to write strong scientific proposals, develop independence, and grow with confidence as a researcher.

“New technologies can always be learned. What matters most is your attitude and your potential to grow.”

Q: What are some strong points in an application or interview for a postdoctoral position? What should applicants avoid?

A strong application begins with a well-prepared CV that highlights your relevant research experience, fellowships, participation in projects, and outputs such as publications, conference presentations, or awards. Teaching experience and academic recognitions can also strengthen your profile.

It’s important to show motivation - that you are genuinely interested in the research line of the group and can explain how this postdoc will contribute to your future career. Tell reviewers why you are a good fit by describing your goals and how they align with the position.

Avoid underselling yourself or expressing uncertainty about being ready. Remember: new technologies can always be learned. What matters most is your attitude and your potential to grow.

“Be confident in your potential and persistent in your goals. Every successful researcher has faced rejection and learned from it.”

Q: When evaluators look at a CV for a postdoctoral grant, what are they expecting to see?

They expect a clear narrative of your scientific development. For a first postdoc, evaluators understand that your PhD work might not yet be fully published. In that case, emphasize your experience and the skills you have acquired.

For a second postdoc, your thesis should already be published, and the focus should shift to your postdoctoral experience - even if the results are not yet out. Evaluators want to see continuity, productivity, and clear progression in your scientific maturity.

Q: For someone preparing their first grant as a principal investigator (PI), should the topic be different from their postdoctoral research?

Your first grant can absolutely be related to your postdoctoral research if you feel comfortable in that area. However, it must bring something new — new questions, new approaches, and a clear demonstration of independence from your postdoctoral supervisor.

Even if you remain in the same laboratory, your proposal should make your scientific autonomy evident. Once funded, you should also ensure that the resulting publications list you as the corresponding author.

Q: How ambitious should a first independent project be? What aspects deserve special attention?

Ambition is important, but it must be realistic. The scale of your project should fit the size and resources of your team. If you are working mostly on your own, make sure the objectives are achievable within the available budget and timeframe.

Feasibility - both logistical and financial - is key. At the same time, reviewers appreciate when proposals include cutting-edge technologies or innovative elements. Always verify that your project aligns with the call’s objectives and thematic priorities.

Remember that reviewers assess not only the science but also the PI’s CV, the team, and the potential impact - especially in biomedical research, where translational and patient benefits are valued.

“Start early, seek feedback, and always check that your proposal truly fits the call.”

Q: What advice would you give for writing a first project proposal as PI?

Start early - ideally several months before the deadline, or even longer if you are applying for large grants such as ERC Starting Grants. Reserve plenty of time for feedback and revision.

Understand the call in detail and constantly check that your proposal matches the listed criteria. Clarity is essential: choose a concise, accessible title and an abstract that can be understood even by non-specialized reviewers.

Write in a clear, direct style with short sentences. The limited space is a good thing - it forces you to focus on the essentials.

Don’t be afraid to “sell yourself”: include a complete CV and, when possible, explain the relevance of your most important papers, especially as evaluation systems move away from journal impact factors (as encouraged by DORA).

In the research plan, balance high risk and high gain with feasibility. Clearly describe the state of the art, your hypothesis, objectives, and work plan. Define milestones and deliverables, include a Gantt chart, and explain the expertise of each team member.

Finally, don’t forget aspects such as dissemination, ethics, gender balance, and technology transfer - these are increasingly important in modern grant evaluations.

Q: Any final words of encouragement for early-career scientists?

Be confident in your potential and persistent in your goals. Every successful researcher has faced rejection and learned from it. Preparing a proposal is not only about getting funding - it’s a process that strengthens your ability to think critically, plan effectively, and communicate your science. These skills will serve you throughout your career.

“Preparing a proposal is not only about getting funding - it’s a learning process that will serve you throughout your career.”

We thank Dr. Isabel Fabregat for sharing her inspiring insights with the SFRR-E ECR community. Her practical advice and generous mentorship continue to guide many young scientists on their journey toward independence and scientific excellence.

 

Summary of November's webinar:

On November’s webinar we learnt about ”Mitochondrial dysfunction and redox homeostasis” with two wonderful talks by Michaela Veliova and Christopher Carlein. If you didn’t have a chance to follow the webinar, here’s a summary for you.


Cardiac Mitochondrial Heterogeneity and Bioenergetics Are Shaped by Intracellular Ribosome Distribution

Michaela Veliova, PhD

Spanish National Center for Cardiovascular Research (CNIC), Spain

Michaela Veliova’s project explored how cardiac mitochondrial heterogeneity and bioenergetics are shaped by intracellular ribosome distribution. Cardiomyocyte mitochondria are segregated into two populations, interfibrillar mitochondria (IFM) and subsarcolemmal mitochondria (SSM), which differ in morphology, protein composition and bioenergetic capacity. However, the mechanisms establishing and maintaining these specialized mitochondrial populations remain largely unknown. Through proteomic analyses, Michaela identified distinct cytoplasmic ribosomal proteins associated with each mitochondrial population, suggesting that localized translation may contribute to their functional differences. Notably, she found that the myocyte specific ribosomal protein RPL3L is enriched in the IFM fraction. Loss of RPL3L altered IFM fuel preference and bioenergetic capacity, highlighting its role in maintaining mitochondrial specialization. Moreover, she showed that RPL3L expression was significantly reduced in aged hearts, which correlated with impaired IFM function. These findings suggest that ribosomal protein distribution influences mitochondrial identity and may offer new insights into the molecular basis of cardiac aging.


Adaptive Mechanisms in Pancreatic Islets Counteract Mitochondrial Dysfunction in Barth Syndrome

Christopher Carlein, PhD

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK

Christopher Carlein’s project examined how adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth Syndrome. Pancreatic islets rely heavily on functional mitochondria to regulate blood glucose levels. Christopher investigated the functionality of pancreatic islets in Barth syndrome, a mitochondrial disorder caused by mutations in the Tafazzin (TAZ) gene that lead to dysfunctional cardiolipin remodelling. Mature cardiolipin is essential for cristae formation in the inner mitochondrial membrane. Using a mouse model of global Taz knockdown (Taz-KD), he found that systemic and islet-specific compensatory mechanisms preserve insulin secretion in vivo in Taz-KD mice. These mechanisms included increased mitochondrial volume, glucose uptake and plasma FGF-21 levels. However, when the direct effects of Taz-KD islets were investigated in vitro, without the influence of systemic adaptations, impaired pancreatic islet functionality was observed, characterized by increased oxidative stress, decreased mitochondrial respiration and insulin secretion. Treatment with recombinant FGF-21 rescued insulin secretion deficiency, highlighting the role of FGF-21 in maintaining islet function and glucose homeostasis.

Together, their presentations highlighted both mechanistic insights and potential interventions linking mitochondrial and redox biology to systemic disease

Remember that you can also watch recordings of the webinars through the SFRR-E intranet!

Want to know more about what we do? You’ll find all the info about the ECR Subcommittee on the SFRR-E website.

For regular updates, follow us on Instagram (@sfrr_ecr), Bluesky (@sfrre-ecr.bsky.social‬) Twitter/X (@SFRR_Europe), and LinkedIn (SFRR-E).

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. - we’d love to hear from you!

- The ECR Subcommittee Team

 

Upcoming Events You Won’t Want to Miss:

SFRR-E Annual Meeting

  • Redox Biology, environmental exposures and lifestyle
  • Mainz, Germany | 3-5 June 2026
  • Abstract submission and registration will open 1 November
  • Call for Symposia and Honorary Lectures deadline: 20 September
  • More info

The Society for Redox Research Australasia & International Human Peroxidase Joint Meeting

  • Christchurch, New Zealand | 3-4 September 2026
  • Abstract deadline: 1 July | Early registration deadline: 17 July
  • More info

17th International Conference on Reactive Oxygen and Nitrogen Species in Plants

  • Granada, Spain | 9-11 September 2026
  • Abstract deadline: 2 May | Registration deadline: 30 June
  • More info

23rd Biennial Meeting of SFRR International 2027

  • Redox Frontiers 2027: Expanding Horizons with New Concepts and Technologies
  • Sendai, Japan | 28-31 March 2027
  • More information coming soon
  • More info

Redox Reads Worth Your Time: 

Research Articles

Zarges, C., Fieler, H., Rothemann, R.A., et al. The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103884

Lange, M., Wölk, M., Li, V.W. et al. FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis. Nat Cell Biol (2025). https://doi.org/10.1038/s41556-025-01790-y

Palma, M., Chaufan, M., Breuer, C.B. et al. Lymph node environment drives FSP1 targetability in metastasizing melanoma. Nature (2025). https://doi.org/10.1038/s41586-025-09709-1

Wu, K., Vaughan, A.J., Bossowski, J.P. et al. Targeting FSP1 triggers ferroptosis in lung cancer. Nature (2025). https://doi.org/10.1038/s41586-025-09710-8

Barnett, D., Zimmer, T.S., Booraem, C. et al. Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01390-y

Serra, M., Smiriglia, A., Migliore, C. et al. Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes. Cell Death Dis (2025). https://doi.org/10.1038/s41419-025-08134-6

Xiao, H., Ordonez, M., Fink, E.C. et al. Covariation MS uncovers a protein that controls cysteine catabolism. Nature 647, 268–276 (2025). https://doi.org/10.1038/s41586-025-09535-5

Shen, T.K., Vignane, T., Gilglioni, E.H., et al. Metabolic dysfunction-associated steatohepatitis reduces hepatic H2S-producing enzymes altering persulfidome composition. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103809

Derismahafi, Z., Farhud, D., Razavirad, A. et al. NRF2 expression level and estrogen function in BRCA1-mutated breast cancer. BMC Cancer (2025). https://doi.org/10.1186/s12885-025-14781-x

Chen, J., Yap, M.C., Bassot, A., et al. The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts. Cell Rep (2025). https://doi.org/10.1016/j.celrep.2025.116486

 

Reviews to Think About

Pan, H., Yin, F. Mitochondrial ROS sources steer neuroinflammation. Nat Metab (2025). https://doi.org/10.1038/s42255-025-01391-x

Qi, Y., Li, Z. & Zuo, Q. Peroxiredoxins: Regulatory Roles and Potential Clinical Significances in Breast Cancer. Free Radic Res (2025). https://doi.org/10.1080/10715762.2025.2592016

  

Preprints We’re Watching

Li, H., Pavlič, A., Ibrahim, N.E., et al. Rewiring protein function through genetically encoded oxidative chemistry. BioRxiv (2025). https://doi.org/10.1101/2025.11.06.686050 

 

Call for Papers:

Journal: Redox Biochemistry and Chemistry

  • Special Issue: Redox Metals in Health and Disease
  • Submission Deadline: 31 December 2025
  • More info

Journal: Redox Biology

  • Special Issue: The role of nitric oxide in redox signaling and disease: shaping the future with emerging leaders
  • Submission Deadline: 31 December 2025
  • More info

 

Redox Jobs Board:

Type of position: PhD position

Type of position: PhD position

Type of position: PhD position

Type of position: Assistant Professor position

  • Research topic: Environmental Impact on Human Metabolic Disease
  • Institute or university: Unversity of California, Berkeley, USA
  • Deadline: 20 December 2025
  • Aditional details: https://aprecruit.berkeley.edu/JPF04710

Type of position: Group Leader

Type of position: Postdoctoral position


Got a position open for a PhD student, postdoc, or technician in redox research?

Want to feature it in our next newsletter? Send us the details at This email address is being protected from spambots. You need JavaScript enabled to view it. including:

  • Type of position (PhD student, Postdoc, etc)
  • Research topic
  • Institute or university
  • Deadline
  • Contact info
  • Additional details or link

October News from the ECR subcommittee

Dear fellow researchers, 

As we dive deep into the autumn season, we’re back with another round of exciting updates from the SFRR-E ECR community!

In this issue, we’re thrilled to announce the speakers for the 3rd PhD Symposium - get ready for an inspiring line-up of emerging redox researchers. We’re also sharing details about the SFRR-E Travel Awards for next year’s SFRR-E Annual Meeting in Mainz, so start planning your abstracts and applications! Plus, don’t miss our recaps of the September and October webinars, full of insightful discussions and take-home tips for ECRs.

And of course, as always, you’ll also find upcoming deadlines, interesting events, paper calls, fresh redox reads, and job opportunities you won’t want to miss.

Good people go…

This time, we say farewell to someone truly special - Carmen Veith.

Carmen has been the Chair of the ECR Subcommittee since its very beginning, and one of the fundamental pillars that made this team what it is today. She was the driving force who got us organized, connected, and running. We are here because of her commitment, enthusiasm, and discipline.

Carmen was involved in everything - from mentoring to events - but she brought even more energy to the conference team and social media, where her creativity and dedication shone through.

She will be greatly missed, not only for her hard work and leadership but also for her hilarious games during our meetings (especially the unforgettable Christmas sessions!). She taught us that one person can be kind, disciplined, funny, and incredibly friendly all at once.

Carmen also reminded us of the value of having a vision beyond academia, and her perspective enriched everything we did as a team.

We wish her all the very best - and much success - in her new role within the SFRR-E Council.

Thank you, Carmen, for everything. You’ll always be part of our redox family.

 

3rd PhD Symposium - Meet the Speakers!

Get ready for the 3rd edition of our PhD Symposium “Redox Relay Race: PhD Students on the Move”, coming up 18 - 19 November 2025!

We’re thrilled to present a fantastic line-up of early-career researchers from around the world who will showcase their cutting-edge work on redox biology in our signature flash talk format.

Day 1 - Tuesday, 18 November 2025, 15:00 CET

Weiwei Li - Wageningen University / Radboud University Medical Center, The Netherlands
Role of Nicotinamide Nucleotide Transhydrogenase (NNT) in cellular redox and energy homeostasis

Lauren McKeever - Leibniz Institute for Plasma Science and Technology (INP), Germany
Modulating Cellular Redox Signalling with Medical Gas Plasma: A Novel Approach to Targeting Actinic Keratosis

Jiayin Zheng - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Pharmacological treatment with cardiovascular or neuroactive drugs as a mitigation strategy against aircraft noise-induced cardiovascular and cerebral damage

Rayen De Fazio - CONICET - National University of La Plata, Argentina
Mitochondrial NHE1 mediates ROS-dependent mPTP opening via hyperpolarization

Yanislav Hrytseniuk - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Impact of CO in shisha smoke/aerosol on health effects in mice - insights from comparison of coal and electric heating

Arijan Valar - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Preadiposity and prediabetes biomarker screening in subchronic aircraft noise exposure mouse models

Shani Doron - The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Israel
Two opposing redox signals mediated by 2-Cys Prx shape the redox proteome during the photosynthetic induction phase

Eva Martín-Prieto – Institute of Neurosciences of Castilla y León (INCYL), Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Spain
Reactive oxygen and nitrogen species (RONS) as regulators of glucose uptake and insulin resistance in diabetes and ageing

Lucas Carvalho - Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Brazil
Sex-dependent effect of aging on NAD⁺ metabolism and redox homeostasis in visceral adipose tissue

 

Day 2 – Wednesday, 19 November 2025, 15:00 CET

Valentin Kapferer - Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
From MAAFs to DAAFs: Improving stability and anticancer activity of aminoferrocene-based ROS catalysts

Manjeera Nath - INRES-Chemical Signalling, University of Bonn, Germany
Decoding the functions of Tau Glutathione transferases in Arabidopsis

Andrea Bianchi – University of L’Aquila, Italy
Resveratrol counteracts redox imbalance and mitochondrial dysfunctions induced by nano and microplastics in human granulosa cells

Sara Melija - University of Ferrara, Italy
ER–mitochondria associated membranes (MAMs) dysfunction in Rett syndrome: investigating calcium signalling alterations and potential therapeutic strategies

Julia Souza - University of São Paulo School of Medicine, Brazil
Exacerbated vascular remodeling in mice overexpressing the dithiol oxidoreductase protein disulfide isomerase-A1

Manuela Hidalgo - Biomedicine Research Institute Sols-Morreale (IIBM, CSIC-UAM), Spain
Loss of mitochondrial plasticity negatively impacts on HCC development in the context of MASLD

Laura Gemmo - University of Ferrara, Italy
Dysregulation of the PI3K/Akt–FoxO3a axis under oxidative or metabolic stress in Rett syndrome

Niki Astropekaki - University of Crete - Institute of Molecular Biology and Biotechnology (IMBB), Greece
Developmental oxidative stress enhances later-in-life immune defences and fitness of the C. elegans host

Giulia Trinchera - University of Ferrara, Italy
Marine red algae as a new technology for preventing UV skin damage

We can’t wait to see these talented PhD researchers share their discoveries and spark new discussions in the redox community! See you at the symposium!

 

SFRR-E Travel Awards - Mainz 2026

Ready to take your science on the road?

We’re excited to announce that SFRR-E Travel Awards will be available for students and postdocs to attend the 2026 SFRR-E Annual MeetingRedox Biology, Environment Exposures and Lifestyle”, taking place in Mainz, Germany (3-5 June 2026).

What’s on offer?

Europe-based applicants: €400 travel grants for PhD students or postdocs (≤5 years post-PhD, non-permanent positions).

Outside Europe: €900 travel awards for SFRR-E or Regional SFRR Society members under the same conditions.

(Note: previous SFRR-E Travel Grant or Young Investigator Award recipients are not eligible.)

Who can apply?

PhD students and postdocs who are current members of SFRR-E (or a Regional SFRR Society outside Europe) and meet the eligibility criteria above.

How to apply

Submit your application as a single PDF via the SFRR-E intranet (https://intranet.sfrr-europe.org) and select the option “Travel Awards for SFRR-E Mainz” in the menu on the left.

Your PDF should include:

    • CV (max 2 pages, including PhD start/award date)
    • Motivation letter
    • Abstract intended for presentation

(Incomplete applications will not be considered.)

Important dates

  • Deadline: 12 January 2026
  • Results announced: before 26 January 2026 (abstract submission deadline)
  • Funds will be transferred after proof of registration and abstract submission.
  • Conference website: www.sfrremainz2026.com
  • Questions? Contact This email address is being protected from spambots. You need JavaScript enabled to view it.

Don’t miss your chance to join us in Mainz - and take your redox research further than ever!

 

Summary of September’s webinar:

On September’s webinar we learnt about ”Redox regulation in cellular aggregates” with two wonderful talks by Avilien Dard and Thibaut Vignane. If you didn’t have a chance to follow the webinar, here’s a summary for you.

Unveiling redox-regulation of protein phase separation during heat stress

Avilien Dard, PhD

Center for Plant Systems Biology, Vlaams Instituut voor Biotechnologie, Ghent University, Belgium

Does the heat stress you? Plants are normally exposed to a wide-range of environmental challenges such as heat. Which, inevitably, will lead to an increase in intracellular reactive oxygen species (ROS). ROS are key signaling molecules that modulate plant responses, but if not detoxified, will cause oxidative damage and ultimately, cell death. In this webinar, Avilien Dard shared with us his work on how ROS generated during heat stress can diffuse within plant cells and particularly oxidize the nucleus earlier than other sub-compartments. He further explored the heat-induced signaling response by characterizing its connection with Histone deacetylase 6 (HDA6), a protein localized in both the nucleus and cytosol, and the observed rise in nuclear ROS. Interestingly, HDA6 appears to be contained in heat-induced stress granules, whose formation appears to be regulated by the cellular redox state. Using genetically encoded fluorescent biosensors, Avilien is now deciphering how these stress granules are more oxidized than their surrounding cytoplasm, providing new insight into redox control during plant heat stress responses.


Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain

Thibaut Vignane, PhD

Institute of Molecular Systems Medicine, Goethe University Frankfurt am Main, Germany

Keeping proteins young with H₂S. Hydrogen sulfide (H₂S), produced by cystathionine gamma lyase (CSE) among other enzymes, have an important role in slowing aging and protecting the organisms against neurodegeneration. Its signalling function depends on protein persulfidation, a post-translational modification (PTM), in which H₂S reacts with cysteine residues, protecting them from irreversible overoxidation. In this webinar, Thibaut Vignane presented a widespread proteomic analysis showing that protein persulfidation declines with age, particularly in brain cells, while oxidative modifications such as sulfenylation and sulfonylation increase. Using mice deficient in CSE, he has demonstrated how the lack of H₂S leads to higher levels of overoxidized cysteines and enhanced protein aggregation. Interestingly, many of the sulfenylated and persulfidated proteins found are also involved in phase-separation, suggesting a link between persulfidation and protein aggregation. Two key candidates arise from his analysis: Synapsin-1 (SYN1) and G3BP2, both critical for neuronal function. In young cells, persulfidation of SYN1 prevents excessive oxidation and protein-aggregation, whereas in aging cells, reduced H₂S levels favour sulfenylation and phase separation. Similarly, sulfenylation of G3BP2 in older cells enhances stress granule formation. Aggregates that can be dissolved by the external addition of H₂S. Thibaut’s findings highlight a pivotal role of H₂S in the redox-dependent shift from protective persulfidation to potentially damaging sulfenylation during aging.

 

Summary of October’s webinar:

On October’s webinar we dove into the fascinating topic of “Redox in Plants” with two outstanding talks by Petr Dvorac and Stephanie Frohn.

Copper-dependent control of iron superoxide dismutase 1 links plant development to oxidative stress resilience

Petr Dvorac, PhD

Department of Biotechnology, Faculty of Science, Palacky University Olomouc, Czech Republic

Balancing metals, balancing ROS. Superoxide dismutases (SODs) are important enzymes that catalyze the dismutation of superoxide radicals (O₂⁻) - by-products of photosynthesis and mitochondrial respiration - into the less reactive, and more stable hydrogen peroxide (H₂O₂). The model plant Arabidopsis thaliana encodes seven SOD isoforms, classified according to their active site cofactors into one manganese SOD (MSD1), three iron SODs (FSD1, FSD2 and FSD3), and three cupper/zinc SODs (CSD1, CSD2 and CSD3). In his presentation, Petr Dvořák highlighted how metal availability, especially copper, governs the balance between these SOD types. When grown in copper-limiting conditions, plants upregulate FSD1 to compensate for the reduced activity of Cu/ZnSODs. Conversely, in copper-rich conditions, the expression of CSD1 and CSD2 increases, compensating the FSD1’s protective role against the oxidative stress-imposed methyl viologen, an herbicide that promotes O₂⁻ production. Together, these findings underscore that FSD1 and CSD2 function as complementary redox protective systems against oxidative stress, and that their abundance is tightly regulated by metal availability. Current research done by Petr, explores possible noncanonical nuclear roles of FSD1, such as involvement in alternative splicing or transcriptional co-activation, expanding our view of how redox enzymes contribute to stress adaptation beyond their classical antioxidant functions.

Role of CuZnSODs on early land plant evolution and development

Stephanie Frohn, PhD

Group Cytoplasmic Inheritance, Department Plant Physiology, WUR Wageningen, Netherlands

Way beyond antioxidants: decoding the moonlighting roles of CSD1. While flowering plants such as Arabidopsis thaliana (Arabidopsis) have three cupper/zinc superoxide dismutases (CSDs), early land plants like the liverwort Marchantia polymorpha (Marchantia) contain only one. In this webinar, Stephanie Frohn explored the multifaceted “moonlighting” functions of CSD1 in Arabidopsis, extending far beyond its classical antioxidant role. Here we learned that CSD1 acts not only as an enzyme dismutating superoxide radical (O₂⁻) into hydrogen peroxide (H₂O₂) but also functions as a developmental regulator during plant embryogenesis and a transcriptional regulator influencing processes such as anthocyanin biosynthesis. Both Marchantia and Arabidopsis displayed strong developmental defects when treated with LCS-1, a broad SOD inhibitor. Developmental phenotypes that were also observed in lines deficient in CSD1 for both plant species. These findings reveal that CSD1 is capable of integrating redox control with developmental and transcriptional regulation, highlighting an evolutionarily conserved role of CSDs in plant growth and stress responses-one that transcends their canonical function as mere antioxidant enzymes.

Remember that you can also watch recordings of the webinars through the SFRR-E intranet!

Want to know more about what we do? You’ll find all the info about the ECR Subcommittee on the SFRR-E website.

For regular updates, follow us on Instagram (@sfrr_ecr), Bluesky (@sfrre-ecr.bsky.social‬) Twitter/X (@SFRR_Europe), and LinkedIn (SFRR-E).

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. - we’d love to hear from you!

- The ECR Subcommittee Team

 

Upcoming Events You Won’t Want to Miss:

SfRBM 2025 - 32nd Annual Conference

  • Society for Redox Biology & Medicine
  • Washington DC | 19–22 November 2025
  • Abstract deadline: 6 September | Early registration deadline: 15 October
  • More info

SFRR-E Annual Meeting

  • Redox Biology, environmental exposures and lifestyle
  • Mainz, Germany | 3–5 June 2026
  • Abstract submission and registration will open 1 November
  • Call for Symposia and Honorary Lectures deadline: 20 September
  • More info

 

Redox Reads Worth Your Time:

Research Articles

Vorhauser, J., Roumeliotis, T.I., Coupe, D., et al. A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision. Mol Cell (2025). https://doi.org/10.1016/j.molcel.2025.07.023

Zarges, C., Fieler, H., Rothemann, R.A., et al. The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness. Redox Biol (2025). https://doi.org/10.1016/j.redox.2025.103884

Wang, YC., Wu, PH., Ting, WC. et al. Single-cell signaling network profiling during redox stress reveals dynamic redox regulation in immune cells. Nat Commun (2025). https://doi.org/10.1038/s41467-025-60727-z

Gotthardt, G., Weckesser, J., Tascher, G., et al. Cysteine-reactive covalent chloro-N-acetamide ligands induce ferroptosis mediated cell death. EMBO Rep (2025). https://doi.org/10.1038/s44319-025-00593-4

Carlein, C., Hoffmann, M.D.A., Bickelmann, C., et al. Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome. Diabetologia (2025). https://doi.org/10.1007/s00125-025-06575-4

Casas-Martinez, J.C., Xia, Q., Li, P. et al. Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly. Cell Death Differ (2025). https://doi.org/10.1038/s41418-025-01603-7


Reviews to Think About

Caporossi, D., Jackson, M.J. & Henriquez-Olguin, C. Intracellular and Extracellular Redox Signals During Exercise and Aging. Free Radic Biol Med (2025). https://doi.org/10.1016/j.freeradbiomed.2025.10.283

Mao, C., Jiang, D., Koong, A.C. et al. Exploiting metabolic cell death for cancer therapy. Nat Rev Cancer (2025). https://doi.org/10.1038/s41568-025-00879-8

Jeria-Espinoza, V., Henriquez-Olguin, C., Opazo-Diaz, E. & Marchini, T. Redox biology at the intersection of physical activity and air pollution: Mechanisms, consequences, and complexity. Free Radic Biol Med (2025). https://doi.org/10.1016/j.freeradbiomed.2025.09.047

Xu, Y., Xie, W. & Zhang, J. Metabolic regulation of key developmental events during mammalian embryogenesis. Nat Cell Biol (2025). https://doi.org/10.1038/s41556-025-01720-y

Margaritelis, N.V. & Nikolaidis, M.G. Science captured by storytelling: the oxidative stress narrative. Trends Mol Med (2025). https://doi.org/10.1016/j.molmed.2025.09.004

 

 

New Protocols

Potekhina, E.S., Bass, D.I., Ezeriņa, D. et al. A color-tailored fluorogenic sensor for hydrogen peroxide. Nat Chem Biol (2025). https://doi.org/10.1038/s41589-025-02036-6

Eid, M., Barayeu, U. & Dick, T.P. Chemogenetic detection and quantitation of H2O2 in living cells. Nat Protoc (2025). https://doi.org/10.1038/s41596-025-01226-9

 

 

Preprints We’re Watching

Meneses-Valdés, R., Gallero, S., Hentze, J., et al. Chemogenetic Mitochondrial H2O2 Generation Triggers Dose-Dependent Skeletal Muscle Wasting Signatures. BioRxiv (2025). https://doi.org/10.1101/2025.08.19.671046

de Souza, I., Marques Andrade, I.A., Porto Freitas, F., et al. HMOX1 controls a heme–ferritin switch that protects cells from ferroptosis. BioRxiv (2025). https://doi.org/10.1101/2025.10.14.682408

Inaba, K., Amagai, Y., Arai, C., et al. Zinc-redox crosstalk regulates proteostasis in the endoplasmic reticulum. Research Square (2025). https://doi.org/10.21203/rs.3.rs-7251469/v1

 

Call for Papers:

Journal: Redox Biochemistry and Chemistry

  • Special Issue: Redox Metals in Health and Disease
  • Submission Deadline: 31 December 2025
  • More info

Journal: Redox Biology

  • Special Issue: The role of nitric oxide in redox signaling and disease: shaping the future with emerging leaders
  • Submission Deadline: 31 December 2025
  • More info


Redox Jobs Board:

Type of position: PhD position

 

 Type of position: PhD position

 

Type of position: PhD position


Type of position: PhD position

 

Got a position open for a PhD student, postdoc, or technician in redox research?

Want to feature it in our next newsletter? Send us the details at This email address is being protected from spambots. You need JavaScript enabled to view it. including:

  • Type of position (PhD student, Postdoc, etc)
  • Research topic
  • Institute or university
  • Deadline
  • Contact info
  • Additional details or link

3rd SFRR-E ECR PhD Symposium - “Redox Relay Race: PhD Students on the Move”

3rd SFRR-E ECR PhD Symposium - “Redox Relay Race: PhD Students on the Move”

Get ready for the 3rd edition of our PhD Symposium “Redox Relay Race: PhD Students on the Move”, coming up 18 - 19 November 2025!

We’re thrilled to present a fantastic line-up of early-career researchers from around the world who will showcase their cutting-edge work on redox biology in our signature flash talk format.

Day 1 - Tuesday, 18 November 2025, 15:00 CET

Weiwei Li - Wageningen University / Radboud University Medical Center, The Netherlands
Role of Nicotinamide Nucleotide Transhydrogenase (NNT) in cellular redox and energy homeostasis

Lauren McKeever - Leibniz Institute for Plasma Science and Technology (INP), Germany
Modulating Cellular Redox Signalling with Medical Gas Plasma: A Novel Approach to Targeting Actinic Keratosis

Jiayin Zheng - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Pharmacological treatment with cardiovascular or neuroactive drugs as a mitigation strategy against aircraft noise-induced cardiovascular and cerebral damage

Rayen De Fazio - CONICET - National University of La Plata, Argentina
Mitochondrial NHE1 mediates ROS-dependent mPTP opening via hyperpolarization

Yanislav Hrytseniuk - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Impact of CO in shisha smoke/aerosol on health effects in mice - insights from comparison of coal and electric heating

Arijan Valar - University Medical Center of the Johannes Gutenberg University Mainz, Germany
Preadiposity and prediabetes biomarker screening in subchronic aircraft noise exposure mouse models

Shani Doron - The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Israel
Two opposing redox signals mediated by 2-Cys Prx shape the redox proteome during the photosynthetic induction phase

Eva Martín-Prieto – Institute of Neurosciences of Castilla y León (INCYL), Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca, Spain
Reactive oxygen and nitrogen species (RONS) as regulators of glucose uptake and insulin resistance in diabetes and ageing

Lucas Carvalho - Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Brazil
Sex-dependent effect of aging on NAD⁺ metabolism and redox homeostasis in visceral adipose tissue

 

Day 2 – Wednesday, 19 November 2025, 15:00 CET

Valentin Kapferer - Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
From MAAFs to DAAFs: Improving stability and anticancer activity of aminoferrocene-based ROS catalysts

Manjeera Nath - INRES-Chemical Signalling, University of Bonn, Germany
Decoding the functions of Tau Glutathione transferases in Arabidopsis

Andrea Bianchi – University of L’Aquila, Italy
Resveratrol counteracts redox imbalance and mitochondrial dysfunctions induced by nano and microplastics in human granulosa cells

Sara Melija - University of Ferrara, Italy
ER–mitochondria associated membranes (MAMs) dysfunction in Rett syndrome: investigating calcium signalling alterations and potential therapeutic strategies

Julia Souza - University of São Paulo School of Medicine, Brazil
Exacerbated vascular remodeling in mice overexpressing the dithiol oxidoreductase protein disulfide isomerase-A1

Manuela Hidalgo - Biomedicine Research Institute Sols-Morreale (IIBM, CSIC-UAM), Spain
Loss of mitochondrial plasticity negatively impacts on HCC development in the context of MASLD

Laura Gemmo - University of Ferrara, Italy
Dysregulation of the PI3K/Akt–FoxO3a axis under oxidative or metabolic stress in Rett syndrome

Niki Astropekaki - University of Crete - Institute of Molecular Biology and Biotechnology (IMBB), Greece
Developmental oxidative stress enhances later-in-life immune defences and fitness of the C. elegans host

Giulia Trinchera - University of Ferrara, Italy
Marine red algae as a new technology for preventing UV skin damage

We can’t wait to see these talented PhD researchers share their discoveries and spark new discussions in the redox community! See you at the symposium!

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. - we’d love to hear from you!

How can I join the webinar?

https://us06web.zoom.us/j/86469731540?pwd=cQW0yK5sNCPXO5sSOcaoBHaZPy2Tu8.1
Passcode: 433382

- The ECR Subcommittee Team

SFRR-E ECR Webinar - November 4th!

Next SFRR-E ECR Webinar - November 4th!

We’re thrilled to keep the momentum going with the third session of the SFRR-E ECR webinar series, “Emerging Leaders in Redox Biology”, coming up on November 4th, 2025! This series is dedicated to showcasing early-career researchers and their innovative contributions to the redox field. Following two inspiring sessions, we’re looking forward to another engaging afternoon of learning, discussion, and connection. This time, we’ll explore the captivating topic of “Mitochondrial dysfunction and redox homeostasis”, featuring two outstanding speakers - Michaela Veliova and Christopher Carlein. Join us at 15:00 CET for an exciting deep dive into cutting-edge redox research!

Cardiac Mitochondrial Heterogeneity and Bioenergetics Are Shaped by Intracellular Ribosome Distribution

Michaela Veliova, PhD

Spanish National Center for Cardiovascular Research (CNIC), Spain

Michaela Veliova is a postdoctoral researcher at the Spanish National Center for Cardiovascular Research (CNIC) in the laboratory of Dr. José Antonio Enríquez. She completed her PhD at the University of California, Los Angeles (UCLA) under the mentorship of Drs. Orian Shirihai and Marc Liesa, where she studied mitochondrial physiology and lipid metabolism in brown adipose tissue. During her doctoral work, she discovered novel mechanisms regulating energy expenditure and helped identify distinct mitochondrial populations with specialized functions. At the CNIC, her research focuses on how mitochondrial heterogeneity arises in cardiomyocytes and how its loss during disease alters cardiomyocyte function and overall heart health.

 

Adaptive Mechanisms in Pancreatic Islets Counteract Mitochondrial Dysfunction in Barth Syndrome

Christopher Carlein, PhD

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, UK

Christopher is a postdoctoral researcher at the University of Oxford at the Oxford Centre for Diabetes, Endocrinology and Metabolism. He studied Biophysics at the Technical University of Kaiserslautern and in his master thesis, he employed transient absorption and fluorescence spectroscopy to study protein-chromophore interactions. He then shifted focus to redox biology and mitochondrial dysfunction in pancreatic islets, completing a PhD at the University of Saarland. His main project was to investigate the consequences of Barth Syndrome on pancreatic islet functionality. Christopher combines molecular biology, microscopy and spectroscopy to investigate fundamental signalling pathways, with a particular interest in redox regulations. Currently, he focuses on GLP1R and GIPR incretin biology to advance diabetes treatments.

Don’t miss this inspiring continuation of the series! Mark your calendars, spread the word, and join us online for a stimulating session! We look forward to seeing you there and to another season of groundbreaking science and lively discussions with the SFRR-E ECR community.

Want to know more about what we do? You’ll find all the info about the ECR Subcommittee on the SFRR-E website.

For regular updates, follow us on Instagram (@sfrr_ecr), Bluesky (@sfrre-ecr.bsky.social‬) Twitter/X (@SFRR_Europe), and LinkedIn (SFRR-E).

Got a question, idea, or just want to say hi? Drop us an email at This email address is being protected from spambots. You need JavaScript enabled to view it. — we’d love to hear from you!

How can I join the webinar?

https://us06web.zoom.us/j/86469731540?pwd=cQW0yK5sNCPXO5sSOcaoBHaZPy2Tu8.1
Passcode: 433382

- The ECR Subcommittee Team

SFRR-E

The Society for Free Radical Research - Europe (SFRR-E) is dedicated to promoting interest in all aspects of research related to Free Radicals in any scientific field.

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Información sobre ley de cookies. Este sitio web utiliza cookies para guardar información en su ordenador. Algunas de estas cookies son necesarias para el correcto funcionamiento de la web. Al utilizar nuestro sitio usted acepta las condiciones de uso y nuestra política de privacidad.