Dear colleagues and friends,

Redox homeostasis is a prerequisite for human health, in which physiological levels of nonradical reactive oxygen species function as primary second messengers to modulate redox signaling by orchestrating multiple redox sensors. However, redox dysregulation leads to biomolecule damage and the subsequent occurrence of various diseases such as cardiovascular pathology, cancer, muscle degeneration, and neurodegeneration.

The FEBS Advanced Lecture Course 'Redox signaling in the physiopathology of the human body' 2026, jointly delivered with SFRR-Europe, aims to address the intricate redox signaling network that has evolved around cellular metabolism, the generation of radical species, and the cellular responses that affect growth and death. The speakers will discuss different aspects of redox signaling involved in both physiological and pathological conditions and how dysfunction of this complex signaling network can be targeted to prevent/slow disease onset and progression. Furthermore, different model systems and methodological approaches, including transcriptomics, metabolomics, and proteomics, will be discussed to provide students with a broader perspective on questions, models, and approaches for future studies.