ECR Webinar Series 2025-2026

Beta-Cell Dysfunction in Diabetes: Redox Mechanisms and Beyond

Eloisa Vilas Boas, PhD

Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of Sao Paulo, Brazil

Assistant Professor at USP, leading research on pancreatic beta-cell pathophysiology and the interplay between redox state and calcium homeostasis. During her PhD she investigated NADPH oxidase-derived ROS in cytokine- and fatty acid-induced beta-cell dysfunction, including a 12-month research stay at Saarland University applying redox imaging with roGFP2-Orp1. Her postdoctoral work at USP's Energy Metabolism Laboratory explored mitochondrial calcium transport as a regulator of hepatic oxidative phosphorylation.

Redox signaling and ferroptosis in cardiovascular complications during chronic kidney disease

Janina Frisch, PhD

Department of Biophysics/Redox Physiology, University of Saarland, Germany

Postdoctoral researcher in Prof. Leticia Prates Roma's group, focused on how redox metabolism and reactive oxygen species govern cellular adaptation in cardio-renal complications, using genetically-encoded redox biosensors and in vivo models. One of her major projects investigates ferroptosis as a therapeutic target for cardiomyopathy in patients with chronic kidney disease.

Insights into the peer review and publication of scientific papers

Mike Davies, Professor

Department of Biomedical Sciences, University of Copenhagen, Denmark

Has worked in the UK (York, Brunel), Australia (Heart Research Institute, Sydney) and Denmark (Copenhagen). Previously Editor-in-Chief of Free Radical Research for 10 years; currently Co-Editor-in-Chief of Redox Biochemistry and Chemistry and Scientific Integrity and Ethics Editor for a group of Elsevier journals including Redox Biology. Former President of SFRR-Australasia, SFRR-International and SFRR-Europe. His research examines protein oxidation and extracellular matrix modification in cardiovascular disease.

Redox modulation in aging mediated by stem cell-derived extracellular vesicles

Cristina Mas-Bargues, PhD

Department of Physiology, School of Medicine, University of Valencia, Spain

Started her research on stem cell aging and oxidative stress, with a PhD in 2017 at the University of Valencia and research stays at UC Berkeley and Albert Einstein College of Medicine. Now Assistant Professor at Valencia, focused on extracellular vesicles from stem cells and their application in regenerative medicine.

Thinking redox outside of the cell: how an ER-resident chaperone governs cellular adhesion and the extracellular matrix

Renato Simoes Gaspar, PhD

State University of Campinas (UNICAMP), Sao Paulo, Brazil

Studied redox regulation of platelet physiology during his PhD at the University of Reading (UK), then researched extracellular thiol isomerase PDIA1 and platelet-endothelium interaction in hyperglycemia at the Heart Institute, University of São Paulo. Now starting an independent lab at UNICAMP focused on the extracellular matrix and cardiovascular disease.

The impact of early-in-life redox signaling in health, aging and disease

Daphne Bazopoulou, PhD

Biology of Stress and Aging Lab, Department of Biology, University of Crete, Greece

Assistant Professor and Group Leader at the University of Crete since 2021, after two postdoc positions at the University of Michigan. Her studies in C. elegans revealed that inter-individual differences in developmental ROS levels contribute to variations in stress resistance and lifespan, and provided the first demonstration of a redox-regulated histone methylation event.

Redox signaling in aging

Helena Cochemé, PhD

Redox Metabolism Group, MRC Laboratory of Medical Sciences, London, UK

UKRI Investigator at the MRC LMS and Honorary Senior Lecturer at Imperial College London. PhD in Biochemistry from Cambridge (MRC Mitochondrial Biology Unit); characterized the mitochondria-targeted H2O2 probe MitoB during her postdoc with Prof. Linda Partridge. Her lab studies redox signaling in aging and metabolic disorders using Drosophila.

Orientation, guidance and tips and tricks for successful grant writing for early career scientists

Isabel Fabregat, PhD

Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain

Discovered that TGF-β induces cell death in hepatocytes via ROS production, proposing it as an inducer of intrinsic apoptosis. Moved to IDIBELL as senior investigator in 2005; created the IT-LIVER consortium in 2013 to study TGF-β as a therapeutic target in liver diseases, with continuous national and European (Marie Curie, COST) funding.

Regulation of cell adhesion and anoikis by S-nitrosylation

Salvatore Rizza, PhD

Redox Biology Group, Danish Cancer Institute, Copenhagen, Denmark

Senior researcher in Giuseppe Filomeni's lab, studying GSNOR, a key enzyme regulating nitric-oxide-modified proteins. Linked GSNOR loss to mitochondrial respiration vulnerabilities in tumors, its age-dependent decline via DNA methylation, and in 2023 showed GSNOR deficiency drives FAK1 hyperactivation in most solid tumors — positioning GSNOR as a novel therapeutic marker.

MYCN Mediates Ferroptosis Sensitivity in MYCN-amplified Cancers

Hamed Alborzinia, PhD

HI-STEM & Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany

Graduated in veterinary medicine before a Molecular Biology PhD at Heidelberg University studying cancer cell metabolism. Now a group leader at HI-STEM/DKFZ, uncovering the metabolic cell death pathway of ferroptosis to identify therapeutic strategies for cancers with MYC deregulation and drug tolerance.

Exploring plant redox landscapes by developing novel NADP redox biosensors

Jan-Ole Niemeier

Universität Münster, Germany

Let it shine: Monitoring plant live dynamic with fluorescent biosensors

José Manuel Ugalde

University of Bonn, Germany