Dear colleagues,
In today's newsletter, we will announce the ECR activities that will take place at the annual SFRR-E Meeting in Istanbul. We will also share with you a summary of May’s “Inter-tissue communication” webinar, in case some of you didn’t have the chance to join. At the end of the newsletter, as always, you can also find a collection of upcoming events with important deadlines and some suggestions of interesting redox reads recently published.
SFRR-E Meeting in Istanbul in June: Events for Early Career Researchers
The next annual meeting of the SFFR-E will take place in Istanbul, 5-7 June 2024 and we have planned multiple exciting events dedicated to ECRs!
1) ECR networking event (Wednesday 5th June at 18:30, Hall 2).
On the first evening of the conference we will be back with another ECR networking event! This activity is ECR-only (students, postdocs and assistant professors). Join us for an opportunity to network with like-minded peers and enhance your conference experience. We will play a hilarious game and we will bring our famous stickers!! Don’t miss out!
2) Meet-the-Professors session (Wednesday 5th June, at 19:30, Hall 2).
On Wednesday evening, after the ECR networking event, there will be a “Meet the Professors” session. This event is open to everybody who wants to join. At this event, a group of invited professors with diverse areas of expertise, is willing to answer all your questions. These are the professors participating, start preparing your questions!
- Clare Hawkins (University of Copenhagen, Denmark)
- Daniela Caporossi (University of Rome "Foro Italico", Italy)
- Giuseppe Valacchi (University of Ferrara, Italy and North Carolina State University, USA)
- Mike Davies (University of Copenhagen, Denmark)
- João Laranjinha (University of Coimbra, Portugal)
- Niki Chondrogianni (National Hellenic Research Foundation, Greece)
- Malcolm Jackson (University of Liverpool, UK)
- Isabel Fabregat (Bellvitge Biomedical Research Institute (IDIBELL), Spain)
- Andreas Daiber (University Medical Center of the Johannes Gutenberg-University, Germany)
3) Sunrise Round Table I: Pillow Talks: From Academia to Industry (Thursday 6th June at 8:00, Hall 2).
On Thursday we will begin the morning with a sunrise round table, open for everybody, that you cannot miss. If you would like to switch to industry or if you have ever wondered what working in industry or academia is like just join us! We have invited a whole panel of experts from both sectors who will be willing to answer each one of your questions!
- Antonio Cuadrado (Autonomous University of Madrid, Spain)
- Giuseppe Valacchi (University of Ferrara, Italy and North Carolina State University, USA)
- Kasia Whysall (University of Galway, Ireland)
- Carmen Veith (Calliditas Therapeutics, Switzerland)
- Sven Terclavers (Zeiss, Germany)
- Mike Lu (Lucid Scientific, USA)
4) Sunrise Round Table II: ROS Measurement: From Bedside to Bench (Friday 7th June at 8:00, Hall 2).
Friday morning, we have prepared something very special for you: a sunrise round table, open for everybody, focused on how to measure ROS. Have you ever wondered which is the best technique to measure ROS in your particular experiments? How do redox sensors work? Redox omics? How to accurately measure mitochondrial ROS? All your questions will be answered, come to give your projects a redox boost!
- Hadley D. Sikes (Massachusetts Institute of Technology, USA)
- Jan Riemer (University of Cologne, Germany)
- Giovanni Mann (King’s College London, UK)
- Michael Davies (University of Copenhagen, Denmark)
- Clare Hawkins (University of Copenhagen, Denmark)
5) ECR-Symposium: H2O2 on the Move: from Sub-cellular Redox Signals to Therapeutic Potential (Friday 7th June at 9:00, Hall 1).
On Friday morning, after the sunrise round table, the ECR subcommittee organized for the first time a symposium within the SFRR-E Annual Meeting, which will be open for everybody. Speakers will be ECRs who are willing to share their work with us. Come to learn what other ECRs around the world are studying!
09:00 - 09:20 David Heppner (University at Buffalo, USA)
Utilizing NOX enzymes as model systems for understanding and designing covalent inhibitors
09:20 – 09:40. Rut Espinosa (IDIBELL Bellvitge Biomedical Research Institute, Spain)
Role of the NADPH oxidase NOX4 in the liver tumor microenvironment
09:40 – 10:00 Carlos Henriquez Olguin (University of Copenhagen, Denmark)
A delicate subcellular hydrogen peroxide compartmentalization is crucial for muscle function and the beneficial effect of exercise
10:00 – 10:15 Carmen Veith (Calliditas Therapeutics, Switzerland)
NADPH oxidase modulators from bench-to bedside: Challenges and opportunities
10:15 – 11:00 Discussion
We are looking forward to welcoming you in Istanbul and to our ECR events!
May’s webinar
On May’s webinar, we enjoyed two inspiring talks on the topic “Inter-tissue communication” by Cristina Mas-Bargues and Renato Simoes Gaspar. If you were not able to attend, you can find the recording of this webinar (and previous ones) in the society’s intranet (https://intranet.sfrr-europe.org).
Please note, there will be no webinar in June, since we will be attending the SFRR-E Meeting in Istanbul. The webinars will start again in autumn! Check out our website for the latest information.
Redox modulation in aging mediated by stem cell-derived extracellular vesicles
Cristina Mas-Bargues, PhD
Department of Physiology, School of Medicine, University of Valencia, Spain
Feeling old? In this webinar, Cristina Mas-Bargues introduced us to parabiosis, where connecting the circulatory systems of two rats—one older and one younger—promotes a reverse aging effect in the older rat and vice versa. This phenomenon is likely mediated by extracellular vesicles (EVs), which act as cargo carriers of various biological components facilitating cellular communication. Dr. Mas-Bargues shared how her research team can isolate Evs from senescent cells and use them to prime healthy cells to better respond to stress conditions by changing the cell’s antioxidant defense, yet not the levels of reactive oxygen species. Conversely, injecting “anti-aging” EVs from young mice into older mice improved tissue function and reduced senescence, particularly in muscle. The team of Dr. Mas-Bargues has managed to identify which miRNAs within the EVs can reverse cellular aging and validated them in vitro. A research effort that highlights the therapeutic potential of EVs in aging and disease.
Thinking redox outside of the cell: how an ER-resident chaperone governs cellular adhesion and the extracellular matrix
Renato Simoes Gaspar, PhD
State University of Campinas (UNICAMP), Sao Paulo, Brazil
Feeling clogged? In this webinar, Renato Simoes Gaspar gave us a deep insight into the multifaceted role of PROTEIN DISULFIDE ISOMERASE A1 (PDIA1) in thrombosis, particularly focusing on their influence on thrombus and platelet formation. Here, he showed us how the presence of PDIA1 on the extracellular surface of endothelial cells and platelets plays a critical role, especially under hyperglycemic conditions where it affects cell binding. He discussed how PDIA1 inhibitors prevent platelet adhesion, which, along with glucose levels, modulate cellular stiffness. The webinar also covered the regulatory role of PDIA1 in collagen responses, enhancing collagen fibrinogenesis and acting as a chaperone reorganizing destabilized Type I collagen at body temperature.
SFRR-E Elections 2024
In May, the SFRR-E Elections for President-Elect, Treasurer, General Secretary, Meeting Officer and ten ordinary members of the Council will take place.
During the period of 1st May until 30th May 2024, members may vote electronically via a secure online voting system within the SFRR-E website (intranet.sfrr-europe.org) for the positions available by election. The results of the elections will be reported at the General Assembly during the SFRR-E Annual Meeting that will be held in Istanbul on 5-7 June 2024.
Today is the last chance to vote in the SFRR-E election. Do not forget to vote!
More information about the ECR Subcommittee can be found on the SFRR-E website (https://www.sfrr-europe.org/index.php/ecr-committee/ecr-committee), while regular updates can be found on X (@SFRR_Europe), Instagram (@sfrr_ecr) and LinkedIn (SFRR-E). For any questions or suggestions you might have, you can contact us via email:
We cannot wait to see you at the annual meeting in Istanbul!
The ECR subcommittee
Upcoming events:
SFRR-E Annual Meeting
5 - 7 June 2024
Location: Istanbul, Turkey
From Molecules to Tissues: Redox Biology in Action
Further information: https://www.redoxistanbul2024.com/
6th International Aryl Hydrocarbon Receptor (AHR) Meeting 2024
12 - 15 June 2024
Location: Düsseldorf, Germany
Deadlines: Registration: 31 May 2024
Further information: https://ahr-2024.de
Thiol-Based Redox Regulation and Signaling Gordon Conference
GRS: 13 - 14 July 2024
Deadline: applications must be submitted by 15 June 2024
Further information: https://www.grc.org/thiol-based-redox-regulation-and-signaling-grs-conference/2024/
GRC: 14 - 19 July 2024
Deadline: applications must be submitted by 16 June 2024
Location: Castelldefels, Barcelona, Spain
Further information: https://www.grc.org/thiol-based-redox-regulation-and-signaling-conference/2024/
11th International Conference on Oxidative Stress in Skin Medicine and Biology
12 - 15 September 2024
Location: Andros Island, Greece, Greece
Deadlines: Abstract Submission: 30 June 2024
Further information: http://oxstress.pharm.uoa.gr
FEBS Advanced Lecture Course
Redox biochemistry: cellular responses and disease relevance
30 September - 6 October 2024
Location: Spetses, Greece
Further information: https://redoxbiochemistry2024.febsevents.org
HNE Club Meeting
Lipid Oxidation: New Biochemical Insights and Clinical Applications
10 - 12 October 2024
Location: Genoa, Italy
Further information: https://www.sfrr-europe.org/media/attachments/2024/03/07/new_hne_flyer.pdf
SfRBM 2024 Conference
31st Annual Conference
20 - 23 November 2024
Location: Savannah, Georgia, USA
Deadlines:
Online Registration & Abstract Submission Open: 10 May 2024
Abstract and Awards Deadline: 15 August 2024
Early Registration Deadline: 2 October 2024
Further information: https://sfrbm.org/meetings/sfrbm-2024/
Insightful Redox Reviews:
Sies, H., Mailloux, R.J. & Jakob, U. Fundamentals of redox regulation in biology. Nat Rev Mol Cell Biol (2024). https://doi.org/10.1038/s41580-024-00730-2
Lastest Redox Preprints:
Cobley, J., Margaritelis, N., Chatzinikolaou, P., Nikolaidis, M., & Gareth Davison, G. Ten "Cheat Codes" for Measuring Oxidative Stress in Humans. Preprints (2024). https://doi.org/10.20944/preprints202405.0729.v1